Sry^AKR/J
Spontaneous Allele Detail

Summary

• Symbol: Sry^AKR/J
• Name: sex determining region of Chr Y; sex-determining region of Chr Y- AKR/J
• MGI ID: MGI:3575651
• Synonyms: AKR Y^DOM, Y^AKR
• Gene: Sry Location: ChrY:2662471-2663658 bp, - strand Genetic Position: ChrY, cytoband p
• Alliance: Sry^AKR/J page

Ovotestis development in Map3k4^tm1Flv/Map3k4⁺ X/Sry^AKR/J embryos, characterised by gonadal poles (brackets) lacking markers of testis development and expressing markers of ovary development

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: AKR/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: This allele contains all the information necessary and sufficient to initiate normal testis development but is conditionally dysfunctional on the C57BL/6 background. (J:44538)

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Sry Mutation: 54 strains or lines available

References

• Original: J:10075 Washburn LL, et al., Normal testis determination in the mouse depends on genetic interaction of a locus on chromosome 17 and the Y chromosome. Genetics. 1989 Sep;123(1):173-9
• All: 8 reference(s)