Hmgb3^tm2Dmb
Targeted Allele Detail

Summary

• Symbol: Hmgb3^tm2Dmb
• Name: high mobility group box 3; targeted mutation 2, David M Bodine
• MGI ID: MGI:3575663
• Gene: Hmgb3 Location: ChrX:70599523-70604261 bp, + strand Genetic Position: ChrX, 36.92 cM, cytoband A1
• Alliance: Hmgb3^tm2Dmb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84890
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-GFP cassette was inserted into the 3' untranslated region of the gene locus. GFP expression was detected in hematopoietic tissues (J:84890)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmgb3 Mutation: 7 strains or lines available

References

• Original: J:84890 Nemeth MJ, et al., Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation. Blood. 2003 Aug 15;102(4):1298-306
• All: 2 reference(s)