Tg(Agrp-cre)1Gsb
Transgene Detail

Summary

• Symbol: Tg(Agrp-cre)1Gsb
• Name: transgene insertion 1, Gregory S Barsh
• MGI ID: MGI:3576074
• Synonyms: AGRP-Cre, Tg.AgrpCre, Tg.AgRP-Cre
• Transgene: Tg(Agrp-cre)1Gsb Location: unknown
• Alliance: Tg(Agrp-cre)1Gsb page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Agrp-cre)1Gsb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Agrp

• Mutation details: Cre recombinase cDNA with an IVSpA sequence was placed immediately upstream of the normal translational initiation site in exon 2 of Agrp in a BAC clone. Cre was expressed in the medial portion of the arcuate nucleus of mutant brains. (J:97407)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Agrp (species not specified) Summary of all recombinase alleles driven by Agrp. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:97407 Xu AW, et al., PI3K integrates the action of insulin and leptin on hypothalamic neurons. J Clin Invest. 2005 Apr 1;115(4):951-958
• All: 38 reference(s)