Tas2r105^tm2Csz
Targeted Allele Detail

Summary

• Symbol: Tas2r105^tm2Csz
• Name: taste receptor, type 2, member 105; targeted mutation 1, Charles S Zuker
• MGI ID: MGI:3576385
• Synonyms: T2R5^-
• Gene: Tas2r105 Location: Chr6:131663524-131664426 bp, - strand Genetic Position: Chr6, 63.53 cM
• Alliance: Tas2r105^tm2Csz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97593
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A reverse-tetracycline dependent transactivator and a floxed PGK-neo replaced the entire coding region. (J:97593)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tas2r105 Mutation: 18 strains or lines available

References

• Original: J:97593 Mueller KL, et al., The receptors and coding logic for bitter taste. Nature. 2005 Mar 10;434(7030):225-9
• All: 1 reference(s)