Tg(ACTA1-cre/ERT2)97.16Mtz
Transgene Detail

Summary

• Symbol: Tg(ACTA1-cre/ERT2)97.16Mtz
• Name: transgene insertion 97.16, Daniel Metzger
• MGI ID: MGI:3576667
• Synonyms: Actin-cre, HSA-Cre-Er^T2, HSA-Cre-ER^T2(tg/0), Tg(ACTA1-cre)97.16Mtz
• Transgene: Tg(ACTA1-cre/ERT2)97.16Mtz Location: unknown
• Alliance: Tg(ACTA1-cre/ERT2)97.16Mtz page

Transgene origin

• Strain of Origin: B6SJLF1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(ACTA1-cre/ERT2)97.16Mtz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  ACTA1 (58)

  Acta1

  (MGI:87902)

• Mutation details: Tamoxifen-dependent Cre-ER^T2 recombinase cDNA was inserted at the human skeletal alpha-actin (ACTA1) transcriptional initiation codon in exon 2 of a 90-kb HSA genomic segment contained in a PAC. Five copies were integrated into the genome in this line. (J:97313)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	ACTA1 (human) Summary of all recombinase alleles driven by ACTA1. Comparative matrix view of recombinase activities Alliance human ACTA1 gene page

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97313 Schuler M, et al., Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse. Genesis. 2005 Apr;41(4):165-70
• All: 46 reference(s)