Tg(Cryaa-TAg,Ins2-CALM1)26Ove
Transgene Detail

Summary

• Symbol: Tg(Cryaa-TAg,Ins2-CALM1)26Ove
• Name: transgene insertion 26, Paul Overbeek
• MGI ID: MGI:3576672
• Synonyms: BamInsCam, Bic, CaMTg, OVE26
• Transgene: Tg(Cryaa-TAg,Ins2-CALM1)26Ove Location: unknown
• Alliance: Tg(Cryaa-TAg,Ins2-CALM1)26Ove page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cryaa-TAg,Ins2-CALM1)26Ove expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  chicken	CALM2 (395855)

• Mutation details: A transgene expressing chicken calmodulin gene under the control of pancreatic beta cell-specific rat insulin II promoter was coninjected with a transgene expressing a truncated form of the SV40 large T antigen under the control of the lens-specific mouse Cryaa promoter. Lines 26 and 29 express both transgenes. (J:97926)

Disease models

Expression

In Structures Affected by this Mutation:

15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97926 Epstein PN, et al., Calmodulin-induced early-onset diabetes in transgenic mice. Cell. 1989 Sep 22;58(6):1067-73
• All: 65 reference(s)