Cartpt^tm1Hmh
Targeted Allele Detail

Summary

• Symbol: Cartpt^tm1Hmh
• Name: CART prepropeptide; targeted mutation 1, Hansen M Hsiung
• MGI ID: MGI:3576858
• Synonyms: Cart^-
• Gene: Cartpt Location: Chr13:100034991-100037191 bp, - strand Genetic Position: Chr13, 52.9 cM, cytoband D1
• Alliance: Cartpt^tm1Hmh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97913
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced with a PGK-neo. Northern blot confirmed absence of transcript in mutant brain tissue. (J:97913)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cartpt Mutation: 15 strains or lines available

References

• Original: J:97913 Asnicar MA, et al., Absence of cocaine- and amphetamine-regulated transcript results in obesity in mice fed a high caloric diet. Endocrinology. 2001 Oct;142(10):4394-400
• All: 5 reference(s)