Morf4l1^tm1Kto
Targeted Allele Detail

Summary

• Symbol: Morf4l1^tm1Kto
• Name: mortality factor 4 like 1; targeted mutation 1, Kaoru Tominaga
• MGI ID: MGI:3576922
• Synonyms: Mrg15^-
• Gene: Morf4l1 Location: Chr9:89973718-89996827 bp, - strand Genetic Position: Chr9, 47.42 cM, cytoband D1
• Alliance: Morf4l1^tm1Kto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97640
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A fragment spanning exon 1 and containing the putative transcription start site(s) and translation initiation site was replaced with a PGK-HPRT. Northern and Western blots of mutant MEFs confirmed lack of mRNA and protein expression, respectively. (J:97640)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Morf4l1 Mutation: 51 strains or lines available

References

• Original: J:97640 Tominaga K, et al., MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol. 2005 Apr;25(8):2924-37
• All: 4 reference(s)