Il16^tm1Korn
Targeted Allele Detail

Summary

• Symbol: Il16^tm1Korn
• Name: interleukin 16; targeted mutation 1, Hardy Kornfeld
• MGI ID: MGI:3576925
• Synonyms: IL-16^-
• Gene: Il16 Location: Chr7:83292033-83394934 bp, - strand Genetic Position: Chr7, 47.43 cM, cytoband D2-D3
• Alliance: Il16^tm1Korn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97739
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence for the mature protein, all of exon 6 and protions of exons 5 and 7, were replaced with a neomycin resistance gene in reverse orientation. The prodomain was left intact. (J:97739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il16 Mutation: 54 strains or lines available

References

• Original: J:97739 Ren F, et al., Pro-IL-16 regulation in activated murine CD4+ lymphocytes. J Immunol. 2005 Mar 1;174(5):2738-45
• All: 5 reference(s)