Nfkbia^tm1Kbp
Targeted Allele Detail

Summary

• Symbol: Nfkbia^tm1Kbp
• Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1, Klaus Pfeffer
• MGI ID: MGI:3577709
• Synonyms: ikba^f
• Gene: Nfkbia Location: Chr12:55536195-55539432 bp, - strand Genetic Position: Chr12, 24.0 cM, cytoband C1-C3
• Alliance: Nfkbia^tm1Kbp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97945
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank the promoter region and the first two exons. (J:97945)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nfkbia Mutation: 19 strains or lines available

References

• Original: J:97945 Rupec RA, et al., Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity. 2005 Apr;22(4):479-91
• All: 11 reference(s)