Dnajc3^tm8663Wcl
Targeted Allele Detail

Summary

• Symbol: Dnajc3^tm8663Wcl
• Name: DnaJ heat shock protein family (Hsp40) member C3; targeted mutation 8663, Warren C Ladiges
• MGI ID: MGI:3578105
• Synonyms: Dnajc3^tm1Wcl, P58-, P58^IPK-, P58^IPK
• Gene: Dnajc3 Location: Chr14:119175388-119219109 bp, + strand Genetic Position: Chr14, 62.6 cM
• Alliance: Dnajc3^tm8663Wcl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98194
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An eGFP-betageo cassette replaced exon 1. Protein was absent in Western blot of mutant MEFs. (J:98194)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dnajc3 Mutation: 25 strains or lines available

References

• Original: J:98194 Ladiges WC, et al., Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK. Diabetes. 2005 Apr;54(4):1074-81
• All: 13 reference(s)