Ajuba^tm1Gdl
Targeted Allele Detail

Summary

• Symbol: Ajuba^tm1Gdl
• Name: ajuba LIM protein; targeted mutation 1, Gregory D Longmore
• MGI ID: MGI:3578221
• Gene: Ajuba Location: Chr14:54804929-54815015 bp, - strand Genetic Position: Chr14, 27.84 cM, cytoband C1
• Alliance: Ajuba^tm1Gdl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98248
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin cassette replaced exon 1. Absence of protein was confirmed in mutants by Western blot analysis of MEFs. (J:98248)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ajuba Mutation: 62 strains or lines available

References

• Original: J:98248 Pratt SJ, et al., The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. J Cell Biol. 2005 Feb 28;168(5):813-24
• All: 4 reference(s)