Ift122^sopb
Chemically induced Allele Detail

Summary

• Symbol: Ift122^sopb
• Name: intraflagellar transport 122; sister of open brain
• MGI ID: MGI:3578529
• Gene: Ift122 Location: Chr6:115830431-115903660 bp, + strand Genetic Position: Chr6, 53.72 cM
• Alliance: Ift122^sopb page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU treatment induced a T-to-C transition mutation in the start codon (p.M1T). Western blot analysis confirms the absence of protein in homozygous embryos at E12.5 and E13.5. (J:168317)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ift122 Mutation: 52 strains or lines available

References

• Original: J:98216 Garcia-Garcia MJ, et al., Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5913-9
• All: 6 reference(s)