Frem2^{Gt(KST252)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Frem2^{Gt(KST252)Byg}
• Name: Fras1 related extracellular matrix protein 2; gene trap KST252, BayGenomics
• MGI ID: MGI:3578640
• Synonyms: Frem2^{Gt(pGT1TMpfs)1Pjsc}, Frem2^{Gt(pGT1TMpfs)1Ucd}, Frem2^KST252, my^KST
• Gene: Frem2 Location: Chr3:53421359-53564776 bp, - strand Genetic Position: Chr3, 25.24 cM
• Alliance: Frem2^{Gt(KST252)Byg} page

Mutation origin

• Mutant Cell Line: KST252
• Germline Transmission: Earliest citation of germline transmission: J:98344
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs Vector Type: secretory trap
• A gene trap vector was inserted into the locus. (J:98344)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  KST252	CC144723 ; (MGI Seq Detail)	5' RACE	Chr3:53555306-53559633 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Frem2 Mutation: 137 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:98344 Jadeja S, et al., Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet. 2005 May;37(5):520-5
• All: 2 reference(s)