Elf5^tm1Plp
Targeted Allele Detail

Summary

• Symbol: Elf5^tm1Plp
• Name: E74-like factor 5; targeted mutation 1, Peter L Pfeffer
• MGI ID: MGI:3578666
• Synonyms: Elf5^-
• Gene: Elf5 Location: Chr2:103242443-103281334 bp, + strand Genetic Position: Chr2, 54.43 cM, cytoband E3
• Alliance: Elf5^tm1Plp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98382
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The insertion of a puromycin resistance cassette into exon 2 interrupted gene function, leaving only 26 amino acids in the protein. (J:98382)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elf5 Mutation: 19 strains or lines available

References

• Original: J:98382 Donnison M, et al., Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development. 2005 May;132(10):2299-308
• All: 4 reference(s)