H1f6^tm1Drab
Targeted Allele Detail

Summary

• Symbol: H1f6^tm1Drab
• Name: H1.6 linker histone, cluster member; targeted mutation 1, Birgit Drabent
• MGI ID: MGI:3578782
• Synonyms: H1t^-
• Gene: H1f6 Location: Chr13:23879794-23880528 bp, + strand Genetic Position: Chr13, 9.88 cM, cytoband A3.2
• Alliance: H1f6^tm1Drab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98592
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced the complete coding sequence. Western blot confirmed absence of protein in mutant mice. (J:98592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H1f6 Mutation: 17 strains or lines available

References

• Original: J:98592 Drabent B, et al., Spermatogenesis proceeds normally in mice without linker histone H1t. Histochem Cell Biol. 2000 Jun;113(6):433-42
• All: 2 reference(s)