Gjd2^tm2Kwi
Targeted Allele Detail

Summary

• Symbol: Gjd2^tm2Kwi
• Name: gap junction protein, delta 2; targeted mutation 2, Klaus Willecke
• MGI ID: MGI:3579104
• Synonyms: Cx36del[LacZ], Cx36lacZ
• Gene: Gjd2 Location: Chr2:113840082-113844100 bp, - strand Genetic Position: Chr2, 57.54 cM, cytoband F3
• Alliance: Gjd2^tm2Kwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98594
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: In this allele, exon 2 was deleted and beta-galactosidase was inserted, resulting in the fusion of the exon 1 coded N-terminal and the beta-galactosidase transcripts. (J:98594)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gjd2 Mutation: 23 strains or lines available

References

• Original: J:98594 Degen J, et al., Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice. J Comp Neurol. 2004 Jun 7;473(4):511-25
• All: 11 reference(s)