Nr2f2^tm2.1Tsa
Targeted Allele Detail

Summary

• Symbol: Nr2f2^tm2.1Tsa
• Name: nuclear receptor subfamily 2, group F, member 2; targeted mutation 2.1, Sophia Y Tsai
• MGI ID: MGI:3579117
• Synonyms: COUP-TFII^flox
• Gene: Nr2f2 Location: Chr7:70001692-70016483 bp, - strand Genetic Position: Chr7, 38.66 cM
• Alliance: Nr2f2^tm2.1Tsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98520
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: Exons 1-3 remained flanked by loxP sites as cre expression resulted in the excision of a neo at the 3' end of the locus. A lacZ remained downstream of the floxed exons. (J:98520)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2f2 Mutation: 28 strains or lines available

References

• Original: J:98520 Takamoto N, et al., COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89
• All: 42 reference(s)