Tnfrsf19^tm1Shmi
Targeted Allele Detail

Summary

• Symbol: Tnfrsf19^tm1Shmi
• Name: tumor necrosis factor receptor superfamily, member 19; targeted mutation 1, Sha Mi
• MGI ID: MGI:3579138
• Gene: Tnfrsf19 Location: Chr14:61201324-61283939 bp, - strand Genetic Position: Chr14, 32.06 cM
• Alliance: Tnfrsf19^tm1Shmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98433
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first two coding exons were replaced with a fusion construct containing human CD2 and the neomycin resistance gene. Loss of transcript was confirmed via RT-PCR of mutant brain samples. (J:98433)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf19 Mutation: 35 strains or lines available

References

• Original: J:98433 Shao Z, et al., TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron. 2005 Feb 3;45(3):353-9
• All: 2 reference(s)