Emx2^tm2(cre)Sia
Targeted Allele Detail

Summary

• Symbol: Emx2^tm2(cre)Sia
• Name: empty spiracles homeobox 2; targeted mutation 2, Shinichi Aizawa
• MGI ID: MGI:3579416
• Synonyms: Emx2^Cre
• Gene: Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
• Alliance: Emx2^tm2(cre)Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98539
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Emx2^tm2(cre)Sia expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Emx2 (MGI:95388)

• Mutation details: A cassette containing a cre recombinase and a floxed neo was inserted into the translational initiation codon. Crossing with Tg(Ebaf-cre)21bHmd resulted in the loss of the neo. (J:98539)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Emx2 (mouse) Summary of all recombinase alleles driven by Emx2. Comparative matrix view of recombinase activities Alliance mouse Emx2 gene page

Expression

In Mice Carrying this Mutation:

20 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Emx2 Mutation: 24 strains or lines available

References

• Original: J:98539 Kimura J, et al., Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium. J Neurosci. 2005 May 25;25(21):5097-108
• All: 24 reference(s)