Tg(MGS1-19375/CFP)2R9Rwb
Transgene Detail

Summary

• Symbol: Tg(MGS1-19375/CFP)2R9Rwb
• Name: transgene insertion 2R9, Robert W Burgess
• MGI ID: MGI:3579426
• Synonyms: AGRIN-CFP, Agrn^CFP2R, Tg(Agrn/CFP)2R9Rwb
• Transgene: Tg(MGS1-19375/CFP)2R9Rwb Location: unknown Genetic Position: Chr8, Syntenic
• Alliance: Tg(MGS1-19375/CFP)2R9Rwb page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(MGS1-19375/CFP)2R9Rwb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Agrn (MGI:87961)	Fusion with CFP

• Mutation details: BAC #19375 (Genome Systems, Inc) containing Agrn, 7 kb of upstream DNA, and 30 kb of downstream DNA was used for the insertion vector. CFP was inserted into the last exon of Agrn via bacterial recombineering to serve as an expression marker. Lines 2R9, 4R24 and 6R16 were generated. (J:118795)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118795 Fuerst PG, et al., Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin. Dev Biol. 2007 Mar 1;303(1):165-80
• All: 2 reference(s)