Nkx2-5^tm3Rph
Targeted Allele Detail

Summary

• Symbol: Nkx2-5^tm3Rph
• Name: NK2 homeobox 5; targeted mutation 1, Richard P Harvey
• MGI ID: MGI:3579480
• Synonyms: Nkx2-5^lacZ
• Gene: Nkx2-5 Location: Chr17:27057638-27063962 bp, - strand Genetic Position: Chr17, 13.6 cM
• Alliance: Nkx2-5^tm3Rph page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98489
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ cassette was inserted in-frame into exon 1. (J:98489)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nkx2-5 Mutation: 21 strains or lines available

References

• Original: J:98489 Stennard FA, et al., Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
• All: 1 reference(s)