Eomes^tm1Jrt
Targeted Allele Detail

Summary

• Symbol: Eomes^tm1Jrt
• Name: eomesodermin; targeted mutation 1, Janet Rossant
• MGI ID: MGI:3579497
• Synonyms: Eomes^-
• Gene: Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
• Alliance: Eomes^tm1Jrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98502
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 4.3 kb genomic fragment containing two-thirds of the T-domain and C-terminal half of the locus was replaced with a PGK-neo cassette. (J:98502)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eomes Mutation: 44 strains or lines available

References

• Original: J:98502 Strumpf D, et al., Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development. 2005 May;132(9):2093-102
• All: 2 reference(s)