Tbx20^tm1.1Sev
Targeted Allele Detail

Summary

• Symbol: Tbx20^tm1.1Sev
• Name: T-box 20; targeted mutation 1.1, Sylvia Evans
• MGI ID: MGI:3579849
• Synonyms: Tbx20^-
• Gene: Tbx20 Location: Chr9:24632108-24685580 bp, - strand Genetic Position: Chr9, 10.25 cM
• Alliance: Tbx20^tm1.1Sev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98516
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was removed via cre-mediated recombination. RT-PCR analysis of mutant heart detected a new, shorter transcript resulting from the stop codon in exon 3 that was created by the excision of exon 2. (J:98516)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx20 Mutation: 36 strains or lines available

References

• Original: J:98516 Cai CL, et al., T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May;132(10):2475-87
• All: 4 reference(s)