Adgrg3^tm1Fwa
Targeted Allele Detail

Summary

• Symbol: Adgrg3^tm1Fwa
• Name: adhesion G protein-coupled receptor G3; targeted mutation 1, Frederick W Alt
• MGI ID: MGI:3579990
• Synonyms: Pb99KO
• Gene: Adgrg3 Location: Chr8:95744320-95771878 bp, + strand Genetic Position: Chr8, 47.12 cM
• Alliance: Adgrg3^tm1Fwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:62512
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All of the coding exons (exons 2-8) were replaced with a neomycin resistance cassette. Northern blot confirmed absence of transcript in mutant ES cells. (J:62512)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrg3 Mutation: 42 strains or lines available

References

• Original: J:62512 Sleckman BP, et al., Cloning and functional characterization of the early-lymphocyte-specific Pb99 gene. Mol Cell Biol. 2000 Jun;20(12):4405-10
• All: 1 reference(s)