Aqp7^tm1Ask
Targeted Allele Detail

Summary

• Symbol: Aqp7^tm1Ask
• Name: aquaporin 7; targeted mutation 1, A S Verkman
• MGI ID: MGI:3580002
• Synonyms: Aqp7^-
• Gene: Aqp7 Location: Chr4:41033074-41048139 bp, - strand Genetic Position: Chr4, 20.83 cM, cytoband B1
• Alliance: Aqp7^tm1Ask page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98734
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 2 was deleted.

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aqp7 Mutation: 24 strains or lines available

References

• Original: J:98734 Hara-Chikuma M, et al., Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation. J Biol Chem. 2005 Apr 22;280(16):15493-6
• All: 1 reference(s)