Tbx20^tm1Akis
Targeted Allele Detail

Summary

• Symbol: Tbx20^tm1Akis
• Name: T-box 20; targeted mutation 1, Andreas Kispert
• MGI ID: MGI:3580099
• Synonyms: Tbx20^-
• Gene: Tbx20 Location: Chr9:24632108-24685580 bp, - strand Genetic Position: Chr9, 10.25 cM
• Alliance: Tbx20^tm1Akis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:98806
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: LacZ cDNA followed by a floxed neo selection cassette was inserted into the start codon in the first exon. RFLP analysis and absence of transcript confirmed successful targeting of the locus. (J:98806)

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx20 Mutation: 36 strains or lines available

References

• Original: J:98806 Singh MK, et al., Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707
• All: 3 reference(s)