Runx1tm3(Runx3)Toku
Targeted Allele Detail
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Symbol: |
Runx1tm3(Runx3)Toku |
Name: |
runt related transcription factor 1; targeted mutation 3, Tsukasa Okuda |
MGI ID: |
MGI:3581528 |
Synonyms: |
AML1-3 |
Gene: |
Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
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Alliance: |
Runx1tm3(Runx3)Toku page
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Germline Transmission: |
Earliest citation of germline transmission:
J:98965
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: cDNA encoding the C-terminal region of Runx3, the polyA signal and a puromycin resistance cassette were inserted to replace the endogenous C-terminus. RT-PCR demonstrated mRNA levels were comparable to wild-type.
(J:98965)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Runx1 Mutation: |
34 strains or lines available
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Original: |
J:98965 Fukushima-Nakase Y, et al., Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development. Blood. 2005 Jun 1;105(11):4298-307 |
All: |
1 reference(s) |
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