Bcl2l1^tm1Ywh
Targeted Allele Detail

Summary

• Symbol: Bcl2l1^tm1Ywh
• Name: BCL2-like 1; targeted mutation 1, You-Wen He
• MGI ID: MGI:3581620
• Synonyms: Bcl-x^fl
• Gene: Bcl2l1 Location: Chr2:152622588-152673648 bp, - strand Genetic Position: Chr2, 75.41 cM, cytoband H1
• Alliance: Bcl2l1^tm1Ywh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99012
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to flank exon 1 and exon 2, containing the initiation codon, with loxP sites. (J:99012)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl2l1 Mutation: 104 strains or lines available

References

• Original: J:99012 Zhang N, et al., The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes. J Immunol. 2005 Jun 1;174(11):6967-73
• All: 5 reference(s)