Apob^tm1Meh
Targeted Allele Detail

Summary

• Symbol: Apob^tm1Meh
• Name: apolipoprotein B; targeted mutation 1, Myron E Hinsdale
• MGI ID: MGI:3581824
• Gene: Apob Location: Chr12:8027648-8066835 bp, + strand Genetic Position: Chr12, 3.53 cM
• Alliance: Apob^tm1Meh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99059
• Parent Cell Line: BK4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: A targeting construct was used to duplicate DNA sequence spanning about 12 kb 5' to exon 1 and to about 0.5 kb 3' of the poly A tail of the locus. (J:99059)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Apob Mutation: 224 strains or lines available

References

• Original: J:99059 Hinsdale ME, et al., Complex control of mouse apolipoprotein B gene expression revealed by targeted duplication. Biochim Biophys Acta. 2005 May 15;1734(2):178-89
• All: 1 reference(s)