Rac3^tm1Idc
Targeted Allele Detail

Summary

• Symbol: Rac3^tm1Idc
• Name: Rac family small GTPase 3; targeted mutation 1, Ivan de Curtis
• MGI ID: MGI:3581887
• Synonyms: Rac3^-
• Gene: Rac3 Location: Chr11:120612296-120614795 bp, + strand Genetic Position: Chr11, 84.46 cM
• Alliance: Rac3^tm1Idc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99180
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ-loxP-neo-loxP cassette replaced the entire coding sequence of the gene. RT-PCR and Northern blot confirmed absence of endogenous transcript in mutant brain samples. (J:99180)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rac3 Mutation: 13 strains or lines available

References

• Original: J:99180 Corbetta S, et al., Generation and characterization of rac3 knockout mice. Mol Cell Biol. 2005 Jul;25(13):5763-76
• All: 17 reference(s)