Senp1^m1Mku
Transgenic Allele Detail

Summary

• Symbol: Senp1^m1Mku
• Name: SUMO1/sentrin specific peptidase 1; mutation 1, Michael R Kuehn
• MGI ID: MGI:3582213
• Synonyms: Senp1^tm1Mku
• Gene: Senp1 Location: Chr15:97936625-97991625 bp, - strand Genetic Position: Chr15, 54.04 cM
• Alliance: Senp1^m1Mku page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:88845
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic
• Mutation: Viral insertion
• Mutation details: This allele carries a retroviral insertion in intron 1 which disrupts an intron enhancer element and resulted in a very low level of transcription of an alternatively spliced isoform lacking the carboxyl-terminal protease active site. RT-PCR revealed a significant reduction of all transcripts in mutants. (J:88845)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Senp1 Mutation: 69 strains or lines available

References

• Original: J:88845 Yamada S, et al., Novel testis- and embryo-specific isoforms of the phosphofructokinase-1 muscle type gene. Biochem Biophys Res Commun. 2004 Apr 2;316(2):580-7
• All: 3 reference(s)