Pitpnb^tm1Vab
Targeted Allele Detail

Summary

• Symbol: Pitpnb^tm1Vab
• Name: phosphatidylinositol transfer protein, beta; targeted mutation 1, Vytas A Bankaitis
• MGI ID: MGI:3582490
• Synonyms: PITPbetadelta::neo*
• Gene: Pitpnb Location: Chr5:111478629-111536225 bp, + strand Genetic Position: Chr5, 53.79 cM, cytoband F
• Alliance: Pitpnb^tm1Vab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85733
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A targeting vector was designed to replace exons A and B, encoding amino acids 66-99, with a neomycin resistance gene. (J:85733)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pitpnb Mutation: 20 strains or lines available

References

• Original: J:85733 Alb JG Jr, et al., Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells. Mol Biol Cell. 2002 Mar;13(3):739-54
• All: 1 reference(s)