Prok2^tm1Qyz
Targeted Allele Detail

Summary

• Symbol: Prok2^tm1Qyz
• Name: prokineticin 2; targeted mutation 1, Qun-Yong Zhou
• MGI ID: MGI:3582623
• Synonyms: PK2^-, Prok2^-
• Gene: Prok2 Location: Chr6:99688260-99703353 bp, - strand Genetic Position: Chr6, 46.29 cM
• Alliance: Prok2^tm1Qyz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99245
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced with a luciferase gene and a PGK-neomycin resistance cassette. In situ hybridization failed to detect transcript in mutant mice. (J:114944)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prok2 Mutation: 12 strains or lines available

References

• Original: J:99245 Ng KL, et al., Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling. Science. 2005 Jun 24;308(5730):1923-7
• All: 5 reference(s)