F11rGt(KST235)Byg
Gene trapped Allele Detail
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Symbol: |
F11rGt(KST235)Byg |
Name: |
F11 receptor; gene trap KST235, BayGenomics |
MGI ID: |
MGI:3583782 |
Synonyms: |
F11rGt(pGT1pfs)1Upn, JAM-A-, Jam-Agt |
Gene: |
F11r Location: Chr1:171265129-171292161 bp, + strand Genetic Position: Chr1, 79.43 cM, cytoband H2
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Alliance: |
F11rGt(KST235)Byg page
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Mutant Cell Line: |
KST235 |
Germline Transmission: |
Earliest citation of germline transmission:
J:127992
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Parent Cell Line: |
E14 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT1TMpf
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Mutation details: A gene trap vector (pGT1TMpfs) insertion resulted in the fusion of the first Ig domain to TMbetageo, an artificial protein created from the transmembrane domain of rat Cd4 joined to the catalytically active domains of betagalactosidase and neomycin genes followed by an IRES and placental alkaline phosphatase reporter cassette. The betagalactosidase and neomycin genes are flanked by Frt sites. The absence of protein product in the endothelium of the aorta was confirmed by immunohistochemistry.
(J:99570)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any F11r Mutation: |
31 strains or lines available
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Original: |
J:99570 Parris JJ, et al., JAM-A expression during embryonic development. Dev Dyn. 2005 Aug;233(4):1517-24 |
All: |
11 reference(s) |
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