Bmp2^tm1Jfm
Targeted Allele Detail

Summary

• Symbol: Bmp2^tm1Jfm
• Name: bone morphogenetic protein 2; targeted mutation 1, James F Martin
• MGI ID: MGI:3583785
• Synonyms: Bmp2^f, Bmp2^floxneo
• Gene: Bmp2 Location: Chr2:133394079-133404805 bp, + strand Genetic Position: Chr2, 65.21 cM
• Alliance: Bmp2^tm1Jfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99582
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to flank exon 3 with loxP sites, and to insert an FRT-flanked Pgk-neo downstream of exon 3. (J:99582)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bmp2 Mutation: 27 strains or lines available

References

• Original: J:99582 Ma L, et al., Generation of a Bmp2 conditional null allele. Genesis. 2005 Jul;42(3):203-6
• All: 25 reference(s)