Lmo2^tm4Thr
Targeted Allele Detail

Summary

• Symbol: Lmo2^tm4Thr
• Name: LIM domain only 2; targeted mutation 4, Terence H Rabbitts
• MGI ID: MGI:3584123
• Synonyms: Lmo2-lacZ, Lmo2^lacZ
• Gene: Lmo2 Location: Chr2:103788331-103812223 bp, + strand Genetic Position: Chr2, 54.46 cM
• Alliance: Lmo2^tm4Thr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:59368
• Parent Cell Line: CCB (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting construct was designed to insert a lacZ-neo into exon 5. Targeted ES cells were targeted a second time with a vector containing a hygromycin resistance gene into the same exon. (J:59368)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmo2 Mutation: 31 strains or lines available

References

• Original: J:59368 Yamada Y, et al., The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):320-4
• All: 3 reference(s)