Nab2^tm1Jmi
Targeted Allele Detail

Summary

• Symbol: Nab2^tm1Jmi
• Name: Ngfi-A binding protein 2; targeted mutation 1, Jeffrey Milbrandt
• MGI ID: MGI:3584132
• Synonyms: Nab2^-
• Gene: Nab2 Location: Chr10:127496787-127502572 bp, - strand Genetic Position: Chr10, 74.6 cM
• Alliance: Nab2^tm1Jmi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99824
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neo was inserted to replace exons 1-6. (J:99824)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nab2 Mutation: 44 strains or lines available

References

• Original: J:99824 Le N, et al., Nab proteins are essential for peripheral nervous system myelination. Nat Neurosci. 2005 Jul;8(7):932-40
• All: 4 reference(s)