Lims1^tm1Ref
Targeted Allele Detail

Summary

• Symbol: Lims1^tm1Ref
• Name: LIM and senescent cell antigen-like domains 1; targeted mutation 1, Reinhard Fassler
• MGI ID: MGI:3584173
• Synonyms: PINCH1^neo
• Gene: Lims1 Location: Chr10:58159288-58260513 bp, + strand Genetic Position: Chr10, 29.31 cM
• Alliance: Lims1^tm1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99800
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin cassette replaced part of exon 3, all of exon 4 and most of intron 5. (J:99800)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lims1 Mutation: 53 strains or lines available

References

• Original: J:99800 Li S, et al., PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage. J Cell Sci. 2005 Jul 1;118(Pt 13):2913-21
• All: 1 reference(s)