Summary |
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Transgene origin |
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Transgene description |
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Phenotypes |
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View phenotypes and curated references for all genotypes (concatenated display).
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Disease models |
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Find Mice (IMSR) |
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Notes |
In situ hybridization with a luciferase cDNA probe detects transgene mRNA only in ameloblasts. Immunohistochemical analysis of four day old incisors using antibodies to the FLAG epitope finds tagged amelogenin restricted to ameloblasts, where it is localized to the cytoplasm, and in the secreted organic enamel matrix. (J:100004)
Several independent founder lines generated from this construct were established; no differences were noted among their phenotypes, and no distinction was made among them. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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