Tg(tetO-Vegfa)90Ala
Transgene Detail

Summary

• Symbol: Tg(tetO-Vegfa)90Ala
• Name: transgene insertion 90, Ann L Akeson
• MGI ID: MGI:3586336
• Synonyms: (tetO)7VEGF, (tetO)7VEGF164⁺, tetOVEGF164
• Transgene: Tg(tetO-Vegfa)90Ala Location: unknown
• Alliance: Tg(tetO-Vegfa)90Ala page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: This transgene contains cDNA for the murine Vegfa isoform VEGF-A164 which was inserted between seven copies of the tetracycline operator (tetO)₇-CMV minimal promoter and the bovine growth factor polyadenylation signals sequence. TetO, when present in cells also carrying a tetracycline transactivator (tTA) or reverse transactivator (rtTA) transgene, is inactivated or activated, respectively, by the administration of tetracycline or its analogue doxycycline. (J:86840)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:86840 Akeson AL, et al., Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung. Dev Biol. 2003 Dec 15;264(2):443-55
• All: 16 reference(s)