Dad1^tm1Kni
Targeted Allele Detail

Summary

• Symbol: Dad1^tm1Kni
• Name: defender against cell death 1; targeted mutation 1, Kiyomasa Nishii
• MGI ID: MGI:3586491
• Synonyms: Dad1^-
• Gene: Dad1 Location: Chr14:54472942-54491386 bp, - strand Genetic Position: Chr14, 27.7 cM
• Alliance: Dad1^tm1Kni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99897
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The insertion of a neo at amino acid 18, upstream from the first membrane-spanning domain, disrupted the ORF. (J:99897)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dad1 Mutation: 9 strains or lines available

References

• Original: J:99897 Nishii K, et al., Abnormalities of developmental cell death in Dad1-deficient mice. Genes Cells. 1999 Apr;4(4):243-52
• All: 1 reference(s)