Gfap^tm5Ito
Targeted Allele Detail

Summary

• Symbol: Gfap^tm5Ito
• Name: glial fibrillary acidic protein; targeted mutation 5, Shigeyoshi Itohara
• MGI ID: MGI:3586492
• Synonyms: Gfap^hwt
• Gene: Gfap Location: Chr11:102778162-102791368 bp, - strand Genetic Position: Chr11, 66.48 cM, cytoband D
• Alliance: Gfap^tm5Ito page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99896
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The first exon was replaced by the human exon cDNA. Northern blot demonstrated the expression level in the mutant was the same as that in wild-type. (J:99896)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gfap Mutation: 48 strains or lines available

References

• Original: J:99896 Takemura M, et al., Distribution of phosphorylated glial fibrillary acidic protein in the mouse central nervous system. Genes Cells. 2002 Mar;7(3):295-307
• All: 1 reference(s)