Apoa5^tm1Hgc
Targeted Allele Detail

Summary

• Symbol: Apoa5^tm1Hgc
• Name: apolipoprotein A-V; targeted mutation 1, Edward M Rubin
• MGI ID: MGI:3586505
• Synonyms: apoa5
• Gene: Apoa5 Location: Chr9:46179931-46183217 bp, + strand Genetic Position: Chr9, 25.37 cM, cytoband B
• Alliance: Apoa5^tm1Hgc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72092
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced the entire locus. Northern blot of mutant mice comfirmed the absence of transcript. (J:72092)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Apoa5 Mutation: 25 strains or lines available

References

• Original: J:72092 Pennacchio LA, et al., An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science. 2001 Oct 5;294(5540):169-73
• All: 11 reference(s)