Smarca5^MommeD4
Chemically induced Allele Detail

Summary

• Symbol: Smarca5^MommeD4
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; modifiers of murine metastable epiallele D4
• MGI ID: MGI:3586551
• Gene: Smarca5 Location: Chr8:81426572-81466088 bp, - strand Genetic Position: Chr8, 38.41 cM
• Alliance: Smarca5^MommeD4 page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Mice carrying Tg(Hba1-Gfp)1Ew were treated with ENU. A single T1921A point mutation in exon 12 results in a W520R amino acid residue change in the helicase domain. (J:122400)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smarca5 Mutation: 49 strains or lines available

References

• Original: J:99816 Blewitt ME, et al., An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7629-34
• All: 3 reference(s)