Prdm1^tm1Masu
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm1Masu
• Name: PR domain containing 1, with ZNF domain; targeted mutation 1, M Azim Surani
• MGI ID: MGI:3586884
• Synonyms: Blimp-1^-
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm1Masu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99994
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre mediated excision was used to remove exon 5, from mice carrying Prdm1^tm2Masu. This resulted in a truncated protein lacking the SET domain, central praline rich domain and Zinc fingers. (J:99994)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 66 strains or lines available

References

• Original: J:99994 Ohinata Y, et al., Blimp1 is a critical determinant of the germ cell lineage in mice. Nature. 2005 Jul 14;436(7048):207-13
• All: 7 reference(s)