Hivep3^tm1Glm
Targeted Allele Detail

Summary

• Symbol: Hivep3^tm1Glm
• Name: human immunodeficiency virus type I enhancer binding protein 3; targeted mutation 1, Laurie H Glimcher
• MGI ID: MGI:3586993
• Synonyms: KRC^-, Shn3^-
• Gene: Hivep3 Location: Chr4:119590982-119992608 bp, + strand Genetic Position: Chr4, 55.51 cM, cytoband D1
• Alliance: Hivep3^tm1Glm page

Trabecular bone and clavicle analysis in various mice with Runx2^tm1Mjo and/or Hivep3^tm1Glm alleles

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100058
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A vector was constructed to replace all of exon 4 with a neomycin resistance cassette. Mutants were shown to lack protein. (J:100058)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hivep3 Mutation: 104 strains or lines available

References

• Original: J:100058 Oukka M, et al., Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells. J Exp Med. 2004 Jan 5;199(1):15-24
• All: 9 reference(s)