Zfpm2^lil
Chemically induced Allele Detail

Summary

• Symbol: Zfpm2^lil
• Name: zinc finger protein, multitype 2; little lung
• MGI ID: MGI:3587413
• Synonyms: Fog2^lil, lil
• Gene: Zfpm2 Location: Chr15:40518438-40967988 bp, + strand Genetic Position: Chr15, 15.74 cM, cytoband C
• Alliance: Zfpm2^lil page

Abnormal pulmonary and diaphragmatic development in the Zfpm2^lil/Zfpm2^lil mouse

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A C to T transition 2 bp after position 301, the splice donor site at the end of exon 3, caused a splicing defect resulting in the insertion of 85 bp of intronic sequence into the transcript and introduces a stop codon that generates a severely truncated protein. (J:100119)
• Inheritance: Not Specified

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfpm2 Mutation: 47 strains or lines available

References

• Original: J:100119 Ackerman KG, et al., Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005 Jul;1(1):e10
• All: 2 reference(s)