Sall4^Gt(XE027)Byg
Gene trapped Allele Detail

Summary

• Symbol: Sall4^Gt(XE027)Byg
• Name: spalt like transcription factor 4; gene trap XE027, BayGenomics
• MGI ID: MGI:3587949
• Synonyms: Sall4-1a,b, Sall4^GT, Sall4^{Gt(pGT1Lxf)1Ucd}
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^Gt(XE027)Byg page

Mutation origin

• Mutant Cell Line: XE027
• Germline Transmission: Earliest citation of germline transmission: J:105332
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: An insertion into exon 2 is predicted to result in a fusion protein between the endogenous protein after amino acid residue 383 and the betageo protein. (J:105332)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XE027	CC177967 ; (MGI Seq Detail)	5' RACE	Chr2:168597686-168598086 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  177 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 145 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:105332 Koshiba-Takeuchi K, et al., Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet. 2006 Feb;38(2):175-183
• All: 3 reference(s)