Espl1^Gt(XL058)Byg
Gene trapped Allele Detail

Summary

• Symbol: Espl1^Gt(XL058)Byg
• Name: extra spindle pole bodies 1, separase; gene trap XL058, BayGenomics
• MGI ID: MGI:3587957
• Synonyms: Espl1^{Gt(pGT0Lxf)1Ucd}, ESPL1^hyp
• Gene: Espl1 Location: Chr15:102204701-102232792 bp, + strand Genetic Position: Chr15, 57.45 cM
• Alliance: Espl1^Gt(XL058)Byg page

Mutation origin

• Mutant Cell Line: XL058
• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf
• The gene trap vector disrupts exon 30 resulting in the disruption of the C terminal 105 amino acids. (J:174926)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XL058	CC325101 ; (MGI Seq Detail)	5' RACE	Chr15:102231623-102232132 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  7 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Espl1^Gt(XL058)Byg

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Espl1 Mutation: 95 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)